Weekly paclitaxel as second-line chemotherapy for advanced or recurrent gastric cancer
نویسندگان
چکیده
منابع مشابه
Weekly paclitaxel as second-line chemotherapy in Japanese patients with advanced gastric cancer.
AIM The use of weekly paclitaxel (wPTX) has become a common practice as second-line chemotherapy in Japanese patients with advanced gastric cancer. The aim of the present study was to assess the efficacy of wPTX. PATIENTS AND METHODS We retrospectively analyzed data from 229 patients with advanced gastric cancer who received wPTX as second-line chemotherapy between March 2001 and January 2011...
متن کاملPaclitaxel combined with capecitabine as first-line chemotherapy for advanced or recurrent gastric cancer
Chemotherapy is of crucial importance in advanced gastric cancer (AGC) patients, in order to obtain palliation of symptoms and improve survival. To date, no standard chemotherapy regimen has been established for AGC. The purpose of the present study was to evaluate the efficacy and toxicity of the combination regimen of paclitaxel and capecitabine (PX) as first-line chemotherapy in patients wit...
متن کاملA phase II study of weekly paclitaxel as second-line chemotherapy for advanced gastric Cancer (CCOG0302 study).
BACKGROUND Although paclitaxel was given triweekly in phase II trials prior to its approval for gastric cancer in Japan, it is currently more often delivered by a weekly schedule in the second-line setting. PATIENTS AND METHODS A phase II trial with response rate as the primary end-point was conducted. Patients with metastatic or unresectable gastric adenocarcinoma who had measurable lesions ...
متن کاملNeutropenia as a prognostic factor in advanced gastric cancer patients undergoing second-line chemotherapy with weekly paclitaxel.
BACKGROUND Neutropenia during chemotherapy has been reported to be a predictor of better survival in patients with several types of cancers, although there are no reports in pretreated patients. METHODS We retrospectively analyzed 242 patients with advanced gastric cancer (AGC) who received weekly paclitaxel (Taxol) as second-line chemotherapy. Background characteristics and neutropenia as ti...
متن کاملA phase II study of weekly paclitaxel and doxifluridine combination chemotherapy for advanced/recurrent gastric cancer.
BACKGROUND Paclitaxel and doxifluridine (5'-DFUR) have distinct mechanisms of action and toxicity profiles. This study evaluated the antitumor activity and toxicities of combination chemotherapy with these drugs in patients with advanced/recurrent gastric cancer (AGC). PATIENTS AND METHODS Patients with histologically confirmed AGC, which was either unresectable or metastatic, were included i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gastric Cancer
سال: 2006
ISSN: 1436-3291,1436-3305
DOI: 10.1007/s10120-005-0351-6